Thiourea

Thiourea

SCHEMBL15399733

CC(=O)N(C(C)=O)C(=O)c1ccccc1.NC(N)=S

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
HSD17B10 Q99714 2/20 0.45
POLB P06746 2/20 0.45
CYP3A4 P08684 1/20 0.45
PARP1 P09874 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 5/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
TRPM8 Q7Z2W7 2/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 1/20 0.41
ATM Q13315 1/20 0.41
METTL3 Q86U44 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9725154 0.90 CES2 (0.50) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL11589556 0.86 TDP1 (0.46) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL6267389 0.82 TSHR (0.50) MAPTHSD17B10POLBCYP3A4PARP1
Ethylene SCHEMBL28318847 0.78 TSHR (0.46) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL29155491 0.78 CES2 (0.43) MAPTPOLBTSHRTDP1L3MBTL1
SCHEMBL27645357 0.78 TDP1 (0.46) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL3454381 0.78 MAPT (0.42) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL27813913 0.78 MEN1 (0.49) MAPTHSD17B10L3MBTL1ALDH1A1HPGD
SCHEMBL23069337 0.77 ALDH1A1 (0.46) MAPTHSD17B10POLBCYP3A4PARP1
SCHEMBL4125957 0.77 TDP1 (0.54) MAPTHSD17B10POLBCYP3A4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590311-B2 Accelerators for two part curable compositions Henkel IP & Holding GmbH (DE) 2020-03-17 US disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
EP-2866798-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2015-05-06 EP disclosed
EP-2867319-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS Henkel US IP LLC (US) 2015-05-06 EP disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed
WO-2014004309-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS Henkel US IP LLC (US) 2014-01-03 WO disclosed
WO-2014004311-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS Henkel US IP LLC (US) 2014-01-03 WO disclosed
US-20140004354-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed
US-20140004366-A1 ACCELERATOR/OXIDANT/PROTON SOURCE COMBINATIONS FOR TWO PART CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2014-01-02 US disclosed
US-20140000807-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed
US-20140004353-A1 ACCELERATORS FOR CURABLE COMPOSITIONS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed