Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL15399733 | 0.90 | MAPT (0.45) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL11589556 | 0.87 | TDP1 (0.46) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL29155491 | 0.87 | CES2 (0.43) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL1574223 | 0.85 | CES1 (0.55) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL29045863 | 0.84 | CES2 (0.48) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL17712467 | 0.82 | CES2 (0.39) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL29156746 | 0.82 | AKT1 (0.47) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL6551367 | 0.82 | CES2 (0.46) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL6280366 | 0.80 | CES1 (0.50) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL18919366 | 0.80 | AKR1C3 (0.57) | ALDH1A1HPGDTSHRHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142241-A1 | Dihydroxybenzamide derivatives having anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-22 | — | — | EP | claimed |
| US-5140020-A | Antiinflammatory agents | KUREHA KAGATU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-18 | — | — | US | disclosed |
| US-4725598-A | Derivative of dihydroxybenzamide and a pharmaceutical composition having an anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0142241-B1 | DIHYDROXYBENZAMIDE DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0142241-A1 | Dihydroxybenzamide derivatives having anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-22 | — | — | EP | disclosed |