Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.86 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.86 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.86 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.86 |
| ▸ | MAPT | P10636 | 5/20 | 0.86 |
| ▸ | RAF1 | P04049 | 4/20 | 0.86 |
| ▸ | TP53 | P04637 | 3/20 | 0.86 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | GLA | P06280 | 1/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | GFER | P55789 | 1/20 | 0.80 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308320 | 1.00 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL8104080 | 1.00 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL1132001 | 1.00 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL15400824 | 0.94 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL8008805 | 0.94 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL6469341 | 0.93 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL17133350 | 0.91 | MAPT (0.73) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL11923005 | 0.91 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL3455232 | 0.89 | NOX1 (0.77) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL15075610 | 0.88 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140004071-A1 | Thermochromic Dental Material | BROWN WILLIAM STEVEN (US) | 2014-01-02 | — | — | US | disclosed |