Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.77 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.77 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.77 |
| ▸ | RAF1 | P04049 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.64 |
| ▸ | GCGR | P47871 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15400046 | 0.91 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL1308320 | 0.91 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL1132001 | 0.91 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL8104080 | 0.91 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6469341 | 0.87 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15400824 | 0.85 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL8008805 | 0.85 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL10965277 | 0.83 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL17133350 | 0.82 | MAPT (0.73) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15075611 | 0.81 | MAPK13 (0.89) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208204-A1 | Compositions and Methods for Inhibiting Tumor Growth | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-08-16 | — | — | US | disclosed |