Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756606 | 0.92 | ULK1 (0.35) | ULK1ADORA2AADORA2B | |
| SCHEMBL15390288 | 0.92 | LMNA (0.39) | ULK1HDAC6 | |
| SCHEMBL15401037 | 0.88 | ULK1 (0.32) | ULK1ADORA2A | |
| SCHEMBL15400635 | 0.86 | ULK1 (0.33) | ULK1ADORA2AADORA2BCSNK2A1CSNK2A2 | |
| SCHEMBL15390289 | 0.82 | FABP4 (0.30) | — | |
| SCHEMBL15390240 | 0.79 | LMNA (0.38) | HDAC6 | |
| SCHEMBL15401282 | 0.78 | ULK1 (0.30) | ULK1 | |
| SCHEMBL15522207 | 0.75 | — | — | |
| SCHEMBL15400634 | 0.75 | — | — | |
| SCHEMBL17689377 | 0.71 | PTGS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850086-B1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-07-05 | — | — | EP | disclosed |
| EP-2850086-B1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20200256798-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2020-08-13 | — | — | US | disclosed |
| US-20200256798-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2020-08-13 | — | — | US | disclosed |
| US-10458915-B2 | Heteroarylcyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-10458915-B2 | Heteroarylcyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140080127-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140005404-A1 | Heteroarylcyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10458915-B2 | Heteroarylcyanine dyes | SLC7A5, SLC7A1, SLC67A1 | ULK1 4105/4885ADORA2A 654/4885ADORA2B 2123/4885 |
| US-20200256798-A1 | HETEROARYLCYANINE DYES | SLC7A5, SLC7A1, SLC67A1 | ULK1 4105/4885ADORA2A 654/4885ADORA2B 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.