Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.68 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.68 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.68 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.68 |
| ▸ | RAF1 | P04049 | 5/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114499 | 0.95 | MAPK13 (0.76) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL10600871 | 0.89 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL10078946 | 0.88 | MAPK13 (0.86) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL381791 | 0.88 | MAPK13 (0.67) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL30514842 | 0.88 | MAPK13 (0.67) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL24043905 | 0.82 | MAPK13 (0.76) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL22507473 | 0.81 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL12968277 | 0.78 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9665488 | 0.77 | MAPK13 (0.47) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL26110700 | 0.77 | MAPK13 (0.57) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140004071-A1 | Thermochromic Dental Material | BROWN WILLIAM STEVEN (US) | 2014-01-02 | — | — | US | disclosed |