SCHEMBL10078946

SCHEMBL10078946

Clc1ccccc1-c1[nH]c(-c2ccccc2)nc1-c1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 12/20 0.86
MAPK12 P53778 12/20 0.86
MAPK11 Q15759 12/20 0.86
MAPK14 Q16539 12/20 0.86
RAF1 P04049 9/20 0.86
MAPK9 P45984 2/20 0.57
GCGR P47871 3/20 0.55
MGAM O43451 1/20 0.54
NOX1 Q9Y5S8 1/20 0.51
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
BRAF P15056 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24043905 0.94 MAPK13 (0.76) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL22507473 0.93 MAPK14 (0.76) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL8114499 0.93 MAPK13 (0.76) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL15401233 0.88 MAPK14 (0.68) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL30514842 0.87 MAPK13 (0.67) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL1040038 0.87 MAPK13 (0.67) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL29360656 0.87 MAPK13 (0.67) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL306063 0.87 MAPK13 (0.67) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL381791 0.87 MAPK13 (0.67) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL24043881 0.81 MAPK13 (0.60) MAPK13MAPK12MAPK11MAPK14RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8278387-B2 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2012-10-02 US disclosed
US-8273520-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORPORATION (JP) 2012-09-25 US disclosed
US-20120082836-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-7790348-B2 Decomposable resin composition and flexographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2010-09-07 US disclosed
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7741011-B2 Polymerizable composition and planographic printing plate precursor using the same, alkali-soluble polyurethane resin, and process for producing diol compound FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20100075118-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100068470-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-03-18 US disclosed
US-7645565-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-20090053653-A1 POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-7491487-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed
US-7449282-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-11-11 US disclosed
US-7435529-B2 Photosensitive composition and image recording method using the same FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed
US-7422837-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-7396634-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-07-08 US disclosed
US-7306894-B2 Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-20070231737-A1 polymer having a carbon-carbon unsaturated bond in then chain and a side chain; butadiene-styrene copolymer; thick layer efficiently engraved with low laser energy; sensitivity FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND PAH, RPN1, RER1 MAPK13 1573/4885MAPK12 2450/4885MAPK11 1364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.