Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600871 | 0.80 | MAPK14 (0.59) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL15401233 | 0.77 | MAPK14 (0.68) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL8114499 | 0.76 | MAPK13 (0.76) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL381791 | 0.69 | MAPK13 (0.67) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL30514842 | 0.69 | MAPK13 (0.67) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL22507473 | 0.69 | MAPK14 (0.76) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL10078946 | 0.69 | MAPK13 (0.86) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL31429099 | 0.67 | NPC1 (0.47) | KDM4EALDH1A1NPC1RAB9AGPR55 | |
| SCHEMBL8105110 | 0.67 | ALDH1A1 (0.50) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL1172425 | 0.66 | KDM4E (0.60) | MAPK13RAF1MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519996-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013876-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |