SCHEMBL15401546

SCHEMBL15401546

COC(=O)C(O)c1ccccc1COc1cc(C)c(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
RAB9A P51151 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
FABP4 P15090 2/20 0.39
FABP5 Q01469 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
FFAR4 Q5NUL3 4/20 0.38
FFAR1 O14842 2/20 0.38
CD274 Q9NZQ7 3/20 0.37
ANO1 Q5XXA6 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
KMT2A Q03164 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
RECQL P46063 1/20 0.35
LPAR1 Q92633 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9667108 0.88 MRGPRX4 (0.45) MAPTRAB9AFFAR4FFAR1CD274
SCHEMBL9667104 0.88 MRGPRX4 (0.45) MAPTRAB9AFFAR4FFAR1CD274
SCHEMBL3497245 0.88 SMN1; SMN2 (0.48) PTGDR2ALDH1A1GAAKMT2ALPAR1
SCHEMBL15375527 0.87 FABP4 (0.52) MAPTRAB9ANPSR1FABP4FABP5
SCHEMBL15375470 0.87 RXRA (0.45) NPSR1FABP4FABP5ALDH1A1RECQL
SCHEMBL15402172 0.86 MAPT (0.43) MAPTRAB9ANPSR1FABP4FABP5
SCHEMBL15375369 0.86 PTGDR2 (0.43) MAPTRAB9ANPSR1FABP4FABP5
SCHEMBL15402163 0.83 MAOB (0.41) CD274
SCHEMBL15375381 0.83 MAPT (0.45) MAPTNPSR1FABP4FABP5ALDH1A1
SCHEMBL15402454 0.82 FFAR1 (0.40) MAPTNPSR1FABP4FABP5FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA MAPT 3967/4885RAB9A 1780/4885NPSR1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.