SCHEMBL3497245

SCHEMBL3497245

COC(=O)C(O)c1ccccc1COc1cc(C)ccc1C

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
LPAR1 Q92633 1/20 0.43
ALDH1A1 P00352 2/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
GAA P10253 1/20 0.41
CYP2C9 P11712 1/20 0.41
POLB P06746 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9667108 0.90 MRGPRX4 (0.45) SMN1; SMN2LMNALPAR1ALDH1A1TSHR
SCHEMBL9667104 0.90 MRGPRX4 (0.45) SMN1; SMN2LMNALPAR1ALDH1A1TSHR
SCHEMBL15402290 0.90 TSHR (0.43) SMN1; SMN2HTTLMNAALDH1A1PTGDR2
SCHEMBL27855201 0.88 CYP2C9 (0.42) SMN1; SMN2HTTLMNALPAR1ALDH1A1
SCHEMBL15402009 0.88 PTGDR2 (0.41) SMN1; SMN2HTTLMNALPAR1ALDH1A1
SCHEMBL4241913 0.88 FABP4 (0.50) SMN1; SMN2HTTLMNAALDH1A1PTGDR2
SCHEMBL15401546 0.88 MAPT (0.41) LPAR1ALDH1A1PTGDR2KMT2AGAA
SCHEMBL15375470 0.87 RXRA (0.45) ALDH1A1TDP1POLBKDM4E
SCHEMBL15402404 0.87 TSHR (0.43) SMN1; SMN2HTTLMNAALDH1A1PTGDR2
SCHEMBL15375529 0.87 PTGDR2 (0.41) SMN1; SMN2HTTLMNALPAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101849000-B Reductase, gene thereof and method of using the same SUMITOMO CO LTD 2013-07-03 CN claimed
CN-101679967-B Reductase, gene thereof, and method for using same SUMITOMO CHEMICAL CO 2013-06-12 CN claimed
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2138578-A1 REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-12-30 EP disclosed
CN-1176918-C Alpha-substituted benzene acetic acid its preparation and farm pesticide containing said compound ��Ұ����ҩ��ʽ���� 2004-11-24 CN disclosed
CN-1105703-C Alpha-substituted phenylacetic acid derivatives, their preparation and agricultural fungicides containing the same SHIONOGI & CO (JP) 2003-04-16 CN disclosed
CN-1394846-A Alpha-substituted benzene acetic acid its preparation and farm pesticide containing said compound SHIONOGI & CO (JP) 2003-02-05 CN disclosed
US-6313150-B1 FOR CONTROLLING PHYTOPATHOGENIC FUNGI SHIONOGI & CO., LTD. (JP) 2001-11-06 US disclosed
EP-0754672-B1 GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME SHIONOGI & CO (JP) 2000-10-11 EP disclosed
US-5948819-A α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it SHIONOGI & CO., LTD (JP) 1999-09-07 US disclosed
CN-1145061-A Alpha-substituted phenylacetic acid derivatives, their preparation and agricultural fungicides containing the same SHIONOGI & CO (JP) 1997-03-12 CN disclosed
EP-0754672-A1 GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed