SCHEMBL15401877

SCHEMBL15401877

CCC[Si](OC)(OC)OC(C)(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
TAAR1 Q96RJ0 1/20 0.33
KCNN4 O15554 2/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8978852 0.80 MAPK1 (0.48) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL7057288 0.78 MAPK1 (0.32) MAPK1ALDH1A1ALOX15
SCHEMBL27943115 0.74 MAPK1 (0.45) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL28990191 0.72 MAPK1 (0.44) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL27923955 0.71 TAAR1 (0.36) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL1609512 0.71 CA4 (0.39) L3MBTL1
SCHEMBL19816390 0.71 CA4 (0.39) L3MBTL1
Diphenylether SCHEMBL9580898 0.71 LTA4H (0.54) MAPK1ALDH1A1LMNAHTTL3MBTL1
Aniline SCHEMBL113461 0.71 TSHR (0.44) MAPK1ALDH1A1TAAR1L3MBTL1CYP2C19
SCHEMBL28668696 0.70 TRPA1 (0.36) ALDH1A1ALOX15LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE44695-E1 Dual electrode system for a continuous analyte sensor DEXCOM, INC. (US) 2014-01-07 US disclosed