Diphenylether

Diphenylether

SCHEMBL9580898

CCC[Si](OC)(OC)OC.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.54
TSHR P16473 1/20 0.48
CA4 P22748 1/20 0.44
MAPT P10636 3/20 0.41
ALOX12 P18054 1/20 0.41
HTT P42858 5/20 0.40
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
MAOA P21397 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TTR P02766 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL9580832 0.89 LTA4H (0.56) LTA4HTSHRCA4MAPTALOX12
SCHEMBL19816390 0.84 CA4 (0.39) LTA4HTSHRCA4MAPTALOX12
SCHEMBL1609512 0.84 CA4 (0.39) LTA4HTSHRCA4MAPTALOX12
Diphenylether SCHEMBL9580840 0.83 LTA4H (0.52) LTA4HTSHRCA4HTTNR1H2
Diphenylether SCHEMBL9580825 0.82 LTA4H (0.52) LTA4HTSHRMAPTALOX12HTT
Anthracene SCHEMBL29043801 0.82 CYP1A2 (0.43) TSHRCA4MAPTALDH1A1KMT2A
Diphenylether SCHEMBL9580937 0.81 LTA4H (0.52) LTA4HTSHRMAPTALOX12HTT
Aniline SCHEMBL113461 0.80 TSHR (0.44) TSHRCA4MAPTALDH1A1GAA
SCHEMBL28668696 0.79 TRPA1 (0.36) LTA4HCA4MAPTALDH1A1KMT2A
SCHEMBL7554332 0.78 TDP1 (0.40) LTA4HALOX12ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed