SCHEMBL15410302

SCHEMBL15410302

C=CC(=O)C1(c2ccccc2)CNCCO1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36
TET3 O43151 3/20 0.34
KMT2A Q03164 3/20 0.34
FBXL19 Q6PCT2 3/20 0.34
CXXC5 Q7LFL8 3/20 0.34
KDM2B Q8NHM5 3/20 0.34
CXXC4 Q9H2H0 3/20 0.34
KDM2A Q9Y2K7 3/20 0.34
TET1 Q8NFU7 2/20 0.34
OPRM1 P35372 3/20 0.32
OPRL1 P41146 1/20 0.32
AKT1 P31749 1/20 0.32
SLC6A2 P23975 4/20 0.31
SLC6A3 Q01959 4/20 0.31
SLC6A4 P31645 3/20 0.31
SIGMAR1 Q99720 1/20 0.30
TSHR P16473 1/20 0.30
LMNA P02545 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29240149 0.83 HTR2A (0.41) HTR2AOPRM1OPRL1SLC6A2SLC6A3
SCHEMBL28767790 0.82 HTR2A (0.40) HTR2AOPRM1OPRL1SLC6A2SLC6A3
SCHEMBL2447412 0.81 HTR2A (0.39) HTR2AOPRM1OPRL1SLC6A2SLC6A3
SCHEMBL28745569 0.76 HTR2A (0.40) HTR2AOPRM1SLC6A2SLC6A3SLC6A4
SCHEMBL28805981 0.75 OPRM1 (0.37) HTR2AOPRM1OPRL1SLC6A2SLC6A3
SCHEMBL27460802 0.75 ALDH1A1 (0.35) HTR2AKMT2AOPRM1OPRL1SLC6A2
SCHEMBL4556613 0.73 NPC1 (0.35) KMT2ASIGMAR1LMNA
SCHEMBL3740631 0.70
SCHEMBL3458741 0.68 HTR2A (0.48) HTR2AOPRM1SLC6A2SLC6A3SLC6A4
SCHEMBL136565 0.68 HTR2A (0.41) HTR2AOPRM1SLC6A2SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2865715-B1 RESIN COMPOSITION, OPTICAL FILM FORMED USING SAME, AND POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-02-19 EP claimed
US-9323102-B2 Resin composition, optical film formed using the same, polarizing plate and liquid crystal display device including the same LG CHEM, LTD. (KR) 2016-04-26 US claimed
EP-2865715-A1 RESIN COMPOSITION, OPTICAL FILM FORMED USING SAME, AND POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-04-29 EP claimed
US-20140016196-A1 RESIN COMPOSITION, OPTICAL FILM FORMED USING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME LG CHEM, LTD. (KR) 2014-01-16 US claimed
EP-2865715-B1 RESIN COMPOSITION, OPTICAL FILM FORMED USING SAME, AND POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-02-19 EP disclosed
US-9323102-B2 Resin composition, optical film formed using the same, polarizing plate and liquid crystal display device including the same LG CHEM, LTD. (KR) 2016-04-26 US disclosed
EP-2865715-A1 RESIN COMPOSITION, OPTICAL FILM FORMED USING SAME, AND POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-04-29 EP disclosed
US-20140016196-A1 RESIN COMPOSITION, OPTICAL FILM FORMED USING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME LG CHEM, LTD. (KR) 2014-01-16 US disclosed