Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121045 | 0.65 | TXNRD1 (0.41) | NFE2L2SIGMAR1KDM4ELMNAKMT2A | |
| Acrylic Acid SCHEMBL29034262 | 0.64 | NFE2L2 (0.53) | NFE2L2KDM4ELMNAHPGDKMT2A | |
| SCHEMBL5385849 | 0.64 | HDAC4 (0.37) | HPGD | |
| SCHEMBL5380407 | 0.64 | HDAC4 (0.39) | — | |
| Acrylic Acid SCHEMBL29034269 | 0.63 | NFE2L2 (0.51) | NFE2L2KDM4ELMNAHPGDKMT2A | |
| SCHEMBL29034273 | 0.63 | NFE2L2 (0.51) | NFE2L2KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL4076354 | 0.63 | SIGMAR1 (0.49) | NFE2L2SIGMAR1SMN1; SMN2CYP2D6PDE4B | |
| SCHEMBL19987657 | 0.62 | ALDH1A1 (0.30) | — | |
| SCHEMBL28556152 | 0.62 | NFE2L2 (0.50) | NFE2L2KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL20508124 | 0.61 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | DEVGEN N.V. (BE) | 2009-08-20 | — | — | US | disclosed |
| US-20080146445-A1 | Nematicidal Compositions | DEVGEN NV (BE) | 2008-06-19 | — | — | US | disclosed |
| US-6710017-B2 | Compositions and methods for controlling algae in recirculating water systems | AVECIA, INC. | 2004-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | ACHE, DNPH1, NANP | NPC1 652/4885RAB9A 1840/4885NFE2L2 3055/4885 |
| US-20080146445-A1 | Nematicidal Compositions | ACHE, DNPH1, NANP | NPC1 652/4885RAB9A 1840/4885NFE2L2 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.