Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426849 | 0.87 | ACE (0.47) | MEN1KMT2AGAATDP1CYP3A4 | |
| SCHEMBL16819882 | 0.87 | ACE (0.47) | MEN1KMT2AGAATDP1CYP3A4 | |
| SCHEMBL6957298 | 0.85 | ACE (0.50) | ACE | |
| SCHEMBL6950805 | 0.85 | ACE (0.50) | ACE | |
| SCHEMBL15413210 | 0.81 | CA1 (0.36) | MEN1KMT2AGAASTK17BSTK17A | |
| SCHEMBL22403247 | 0.78 | ACE (0.40) | TDP1ACE | |
| SCHEMBL16844936 | 0.76 | ACE (0.45) | MEN1KMT2AGAATDP1CYP3A4 | |
| SCHEMBL8054432 | 0.76 | CTSS (0.40) | ACE | |
| SCHEMBL13811785 | 0.74 | ACE (0.36) | CYP3A4ACECA1CA2 | |
| SCHEMBL406298 | 0.73 | ATM (0.38) | CYP3A4ACECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872525-A2 | STABILIZED MULTI-FUNCTIONAL ANTIOXIDANT COMPOUNDS AND METHODS OF USE | XPD Holdings LLC (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011624-A2 | STABILIZED MULTI-FUNCTIONAL ANTIOXIDANT COMPOUNDS AND METHODS OF USE | XPD HOLDINGS LLC (US) | 2014-01-16 | — | — | WO | disclosed |