Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15413322 | 0.81 | OPRM1 (0.94) | OPRM1OPRD1ALDH1A1GAAPKM | |
| SCHEMBL23483863 | 0.78 | OPRM1 (1.00) | OPRM1OPRD1ALDH1A1GAAPKM | |
| SCHEMBL20830347 | 0.72 | OPRM1 (0.86) | OPRM1OPRD1ALDH1A1NOD2NOD1 | |
| SCHEMBL20816038 | 0.71 | OPRM1 (0.85) | OPRM1OPRD1ALDH1A1NOD2NOD1 | |
| SCHEMBL15413710 | 0.68 | NSD2 (0.98) | OPRM1NSD2PABPC1CASP6PAX8 | |
| SCHEMBL20816042 | 0.62 | OPRM1 (0.65) | OPRM1OPRD1ALDH1A1NOD2NOD1 | |
| SCHEMBL25015538 | 0.57 | OPRM1 (0.57) | OPRM1OPRD1 | |
| SCHEMBL104068 | 0.55 | DRD2 (0.50) | ALDH1A1GAA | |
| SCHEMBL20305738 | 0.55 | MEN1 (0.54) | OPRM1GAA | |
| SCHEMBL25204350 | 0.55 | ALDH1A1 (0.47) | ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014011540-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-01-16 | — | — | WO | disclosed |