Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602381 | 0.91 | MEN1 (0.54) | KMT2AMEN1THRBMAPTALDH1A1 | |
| SCHEMBL807233 | 0.91 | MEN1 (0.54) | KMT2AMEN1THRBMAPTALDH1A1 | |
| SCHEMBL23705839 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL31091978 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL2498472 | 0.78 | MAPT (0.63) | KMT2AMEN1THRBMAPTALDH1A1 | |
| SCHEMBL807418 | 0.78 | ALDH1A1 (0.58) | KMT2AMEN1MAPTALDH1A1PTPN1 | |
| SCHEMBL5528296 | 0.76 | MAPK1 (0.49) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL2384047 | 0.76 | SIRT6 (0.58) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL19500869 | 0.76 | HIF1A (0.62) | KMT2AMEN1THRBMAPTALDH1A1 | |
| SCHEMBL255446 | 0.75 | CHRNB2 (0.60) | MAPTTGFBR1ACVR1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872506-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009219-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-01-16 | — | — | WO | disclosed |