Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | HTT | P42858 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | APAF1 | O14727 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | RAD52 | P43351 | 3/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.76 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.76 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275162 | 0.99 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL120301 | 0.98 | MEN1 (0.78) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| SCHEMBL3913464 | 0.89 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL1951703 | 0.88 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL122985 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL5549294 | 0.85 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL927612 | 0.85 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL22711570 | 0.85 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL4418328 | 0.85 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A | |
| Benzethonium SCHEMBL1672928 | 0.85 | SMN1; SMN2 (0.98) | SMN1; SMN2LMNAMEN1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809157-B2 | Methods of forming a programmable region that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8633084-B1 | Methods of forming a memory cell having programmable material that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-01-21 | — | — | US | disclosed |