SCHEMBL8883

SCHEMBL8883

Cc1cn([C@H]2CC[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.67
POLB P06746 2/20 0.56
TYMS P04818 1/20 0.54
POLA1 P09884 1/20 0.54
POLD1 P28340 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26757571 1.00 TK1 (0.67) TK1POLBTYMSPOLA1POLD1
SCHEMBL23440065 1.00 TK1 (0.67) TK1POLBTYMSPOLA1POLD1
SCHEMBL28774920 1.00 TK1 (0.67) TK1POLBTYMSPOLA1POLD1
Triphosphate SCHEMBL27892350 0.95 POLB (0.61) TK1POLBTYMSPOLA1POLD1
SCHEMBL13245040 0.92 TK1 (0.57) TK1POLBPOLA1POLD1
SCHEMBL154177 0.91 POLB (0.65) TK1POLBPOLA1POLD1
SCHEMBL16217853 0.91 TK1 (0.56) TK1POLBPOLA1POLD1
SCHEMBL6420653 0.91 TK1 (0.58) TK1POLBPOLA1POLD1
SCHEMBL23440064 0.91 TK1 (0.54) TK1POLBPOLA1POLD1
SCHEMBL14279195 0.90 TK1 (0.55) TK1POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6466 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4610356-A1 RNA INHIBITOR FOR INHIBITING LPA GENE EXPRESSION AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-09-03 EP claimed
CN-120005959-A Method for synthesizing deoxynucleoside triphosphate by enzyme method 上海合全药物研发有限公司 2025-05-16 CN claimed
CN-119855607-A Carbon chain substance for regulating transmembrane transport and fluidity of cell membrane, preparation and application 太阳雨林(北京)生物医药有限公司 2025-04-18 CN claimed
EP-4520348-A1 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF Sunforest (Beijing) Biopharma Ltd (CN) 2025-03-12 EP claimed
CN-119570785-A SiRNA for inhibiting ANGPTL3 gene expression and application thereof 上海民为生物技术有限公司 2025-03-07 CN claimed
CN-119165076-A Method for analyzing random hexamer primer degradation products 生工生物工程(上海)股份有限公司 2024-12-20 CN claimed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 US claimed
EP-3948275-B1 DIAGNOSTIC FOR CHILDHOOD RISK OF AUTISM SPECTRUM DISORDER UNIV ARIZONA STATE (US) 2024-11-13 EP claimed
CN-117264948-B RNAi inhibitor for inhibiting expression of angiotensinogen gene and application thereof 广州必贝特医药股份有限公司 2024-05-10 CN claimed
CN-117264948-A RNAi inhibitor for inhibiting expression of angiotensinogen gene and application thereof 广州必贝特医药股份有限公司 2023-12-22 CN claimed
US-5101024-A DNA sequences, efficient transcription and translation TEIJIN LIMITED (JP) 1992-03-31 US claimed
US-5075227-A DIRECTIONAL CLONING ZYMOGENETICS, INC. (US) 1991-12-24 US claimed
US-5009994-A Uniform distribution EM DIAGNOSTIC SYSTEMS, INC. (US) 1991-04-23 US claimed
WO-1990015814-A1 NUCLEASE RESISTANT, SINGLE-STRANDED, NON-NATURALLY OCCURRING NUCLEIC ACID MOLECULES MEIOGENICS, INC. (US) 1990-12-27 WO claimed
WO-1990010698-A1 DIRECTIONAL CLONING ZYMOGENETICS, INC. (US) 1990-09-20 WO claimed
EP-0183964-B1 DNA SEQUENCE TEIJIN LIMITED (JP) 1990-03-14 EP claimed
US-4786719-A DNA sequence TEIJIN, LIMITED (JP) 1988-11-22 US claimed
EP-0184187-A2 Mouse-human chimaeric immunoglobulin heavy chain, and chimaeric DNA encoding it TEIJIN LIMITED (JP) 1986-06-11 EP claimed
EP-0183964-A1 DNA sequence TEIJIN LIMITED (JP) 1986-06-11 EP claimed
EP-0146743-A2 Gene fragments derived from human immunoglobulin gene TEIJIN LIMITED (JP) 1985-07-03 EP claimed