SCHEMBL15418340

SCHEMBL15418340

CCC1C=C(C)C(=O)CC1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15418365 0.76 NOS1 (0.33) USP2
SCHEMBL15418511 0.74 USP2 (0.36) USP2MEN1ALDH1A1KMT2A
SCHEMBL12087942 0.72 USP2 (0.33) USP2MEN1ALDH1A1KMT2A
SCHEMBL3208597 0.69
SCHEMBL15418719 0.65 NFKB1 (0.38)
SCHEMBL10385319 0.63
SCHEMBL15418433 0.61
SCHEMBL25940420 0.61 USP2 (0.33) USP2MEN1ALDH1A1KMT2A
SCHEMBL3863045 0.61 TAS2R46 (0.30)
SCHEMBL15444632 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687586-B1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes SYMRISE AG (DE) 2016-11-23 EP claimed
US-20140023770-A1 Use Of Defined Cyclohexenones As Agents For The Superadditive Enhancement Of An Olfactory Impression And Fragrance And/Or Flavor Material Composition SYMRISE AG (DE) 2014-01-23 US claimed
EP-2687586-A1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes Symrise AG (DE) 2014-01-22 EP claimed
EP-2687586-B1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes SYMRISE AG (DE) 2016-11-23 EP disclosed
EP-2687586-B1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes SYMRISE AG (DE) 2016-11-23 EP disclosed
US-20140023770-A1 Use Of Defined Cyclohexenones As Agents For The Superadditive Enhancement Of An Olfactory Impression And Fragrance And/Or Flavor Material Composition SYMRISE AG (DE) 2014-01-23 US disclosed
US-20140023770-A1 Use Of Defined Cyclohexenones As Agents For The Superadditive Enhancement Of An Olfactory Impression And Fragrance And/Or Flavor Material Composition SYMRISE AG (DE) 2014-01-23 US disclosed
US-20140023770-A1 Use Of Defined Cyclohexenones As Agents For The Superadditive Enhancement Of An Olfactory Impression And Fragrance And/Or Flavor Material Composition SYMRISE AG (DE) 2014-01-23 US disclosed
EP-2687586-A1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes Symrise AG (DE) 2014-01-22 EP disclosed
EP-2687586-A1 Use of defined cyclohexenones as a means for the additive reinforcement of a smell impression and composition of aromas and/or tastes Symrise AG (DE) 2014-01-22 EP disclosed