Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 16/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951542 | 0.76 | S1PR2 (0.36) | CNR1SCN9A | |
| SCHEMBL9648823 | 0.68 | S1PR2 (0.39) | CNR1 | |
| SCHEMBL9649347 | 0.68 | LMNA (0.38) | SCN9A | |
| SCHEMBL28642079 | 0.68 | CACNA1H (0.38) | GRNSORT1 | |
| SCHEMBL29068145 | 0.67 | CTSK (0.42) | CNR2AAK1 | |
| SCHEMBL15417934 | 0.67 | MAP2K1 (0.41) | CNR2AAK1 | |
| SCHEMBL15418991 | 0.67 | LMNA (0.34) | ACACBACACACNR2CNR1 | |
| SCHEMBL1368673 | 0.67 | S1PR2 (0.40) | — | |
| SCHEMBL29068024 | 0.66 | CTSK (0.41) | CNR2AAK1 | |
| SCHEMBL29053528 | 0.66 | SCN9A (0.31) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687518-B1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-11-01 | — | — | EP | disclosed |
| EP-2687518-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-01-22 | — | — | EP | disclosed |