Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172133 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL597455 | 0.84 | LMNA (0.60) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7318760 | 0.83 | ORAI1 (0.74) | PTGS2PTGS1THRBMAPTTRPC3 | |
| SCHEMBL19692290 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19706476 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2461984 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7397066 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14198876 | 0.82 | TRPC3 (0.69) | PTGS2PTGS1CYP3A4CYP2C9TSHR | |
| SCHEMBL7112386 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22842819 | 0.80 | PTGS2 (0.47) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388408-A | Synthesis method of 3, 5-bis (fluoroalkyl) pyrazole compound | 西北师范大学 | 2024-07-26 | — | — | CN | disclosed |
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-9527807-B2 | Sulfonamide derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20140024650-A1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024650-A1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | GRIN2A, GRIN2B, SLC1A2 | PTGS2 3017/4885PTGS1 3041/4885CYP1A2 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.