Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | ADH5 | P11766 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15419853 | 0.96 | RARB (0.51) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL6252810 | 0.85 | RARB (0.61) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL17369448 | 0.84 | CES2 (0.48) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL30189377 | 0.82 | RARB (0.51) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL26572449 | 0.82 | BCL2L1 (0.62) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL14917120 | 0.82 | RARB (0.51) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL4601444 | 0.81 | RARB (0.49) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL14213193 | 0.81 | LMNA (0.57) | RARBADH5LMNAKDM4EHSD17B10 | |
| SCHEMBL29473809 | 0.80 | RARB (0.56) | RARBADH5LMNAAKR1C3AKR1C2 | |
| SCHEMBL2041007 | 0.80 | RARB (0.56) | RARBADH5LMNAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605207-B2 | Orthoester derivative, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-03-28 | — | — | US | disclosed |
| EP-2690103-A1 | ORTHO ESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-20140021407-A1 | ORTHOESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-01-23 | — | — | US | disclosed |