SCHEMBL15422262

SCHEMBL15422262

Cc1ccc(N(N)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
TSHR P16473 3/20 0.48
ACHE P22303 3/20 0.48
LMNA P02545 1/20 0.48
ALOX12 P18054 1/20 0.48
ALDH1A1 P00352 4/20 0.46
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
TDP1 Q9NUW8 3/20 0.41
CYP2D6 P10635 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41
HIF1A Q16665 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.39
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461295 0.89 ALDH1A1 (0.55) CYP2C19TSHRACHELMNAALOX12
SCHEMBL21763095 0.89 MEN1 (0.44) CYP2C19TSHRACHELMNAALOX12
Hydrochloric Acid SCHEMBL11274539 0.87 ALDH1A1 (0.52) CYP2C19TSHRACHELMNAALOX12
SCHEMBL1792016 0.84 ALDH1A1 (0.46) CYP2C19TSHRALOX12ALDH1A1TDP1
SCHEMBL193916 0.84 ALDH1A1 (0.46) CYP2C19TSHRALOX12ALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL28763213 0.81 ALDH1A1 (0.43) CYP2C19TSHRALOX12ALDH1A1TDP1
Hydrochloric Acid SCHEMBL250009 0.81 ALDH1A1 (0.43) CYP2C19TSHRALOX12ALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL28873134 0.81 ALDH1A1 (0.43) CYP2C19TSHRALOX12ALDH1A1TDP1
Water SCHEMBL8817645 0.81 ALDH1A1 (0.43) CYP2C19TSHRALOX12ALDH1A1TDP1
SCHEMBL9705245 0.80 GAA (0.57) ACHEALDH1A1CA12CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4137551-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-02-22 EP disclosed
CN-115403537-A 2,3,5-trisubstituted-2,3-dihydro-oxatriazole derivative and preparation method thereof 武汉工程大学 2022-11-29 CN disclosed
CN-112409203-B Method for simultaneously synthesizing phenylhydrazine salt and pyruvic acid or glyoxylic acid 帕潘纳(北京)科技有限公司 2022-10-25 CN disclosed
EP-2977378-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-10 EP disclosed
US-9051314-B2 Bridged heterocyclic compounds and methods of use MEDIVATION TECHNOLOGIES, INC. (US) 2015-06-09 US disclosed
US-20140024643-A1 BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE MEDIVATION TECHNOLOGIES, INC. (US) 2014-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140024643-A1 BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE HRH4, HNMT, HTR2C CYP2C19 466/4885TSHR 961/4885ACHE 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.