SCHEMBL9705245

SCHEMBL9705245

Cc1ccc(N(N)c2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.54
HTT P42858 2/20 0.54
CA12 O43570 3/20 0.50
CA9 Q16790 3/20 0.50
HTR6 P50406 2/20 0.50
MAPT P10636 4/20 0.49
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MCOLN3 Q8TDD5 1/20 0.46
POLB P06746 1/20 0.45
KDM4E B2RXH2 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA5B Q9Y2D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891138 0.84 GAA (0.80) GAASMN1; SMN2HTTCA12CA9
SCHEMBL9703223 0.82 ALDH1A1 (0.58) SMN1; SMN2CA12CA9HTR6MAPT
SCHEMBL9704374 0.81 PKM (0.61) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL15422262 0.80 CYP2C19 (0.48) HTTCA12CA9MAPTALDH1A1
SCHEMBL9703408 0.79 HTT (0.60) SMN1; SMN2HTTCA9HTR6CA1
SCHEMBL28747961 0.79 HTR6 (0.53) GAASMN1; SMN2HTTCA12CA9
SCHEMBL12336795 0.79 GAA (0.70) GAASMN1; SMN2HTTCA12CA9
SCHEMBL27713195 0.79 GAA (0.70) GAASMN1; SMN2HTTCA12CA9
(Phenylsulfonyl)Benzene SCHEMBL6912665 0.78 HTR6 (0.74) GAASMN1; SMN2HTTCA12CA9
SCHEMBL15741207 0.78 CA12 (0.69) GAAHTTCA12CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed