SCHEMBL15423181

SCHEMBL15423181

CC1(C)c2cc(-c3ccccc3)cc3ccc4cc(-c5cccc(-c6ccncc6)c5)cc1c4c23

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.44
KIF11 P52732 1/20 0.41
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
MAPK13 O15264 1/20 0.38
GCGR P47871 1/20 0.38
MAPK12 P53778 1/20 0.38
MAPK11 Q15759 1/20 0.38
MAPK14 Q16539 1/20 0.38
PRKCI P41743 1/20 0.37
CYP19A1 P11511 1/20 0.37
KMT2A Q03164 2/20 0.37
KDR P35968 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423167 0.97 NOTUM (0.47) NOTUMKIF11CYP11B1CYP11B2KDM4E
SCHEMBL15423171 0.85 TGFBR1 (0.42) KDM4EALDH1A1MAPTLMNANPSR1
SCHEMBL15423166 0.82 CYP19A1 (0.55) KIF11CYP11B1CYP11B2KDM4EALDH1A1
SCHEMBL15423209 0.82 CYP17A1 (0.44) CYP11B1KDM4EMAPTMAPK14LMNA
SCHEMBL15423202 0.81 CYP11B1 (0.43) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL15423160 0.80 L3MBTL1 (0.43) KDM4EALDH1A1MAPTHPGDCYP19A1
SCHEMBL15423228 0.80 NOTUM (0.39) NOTUMKDM4EALDH1A1MAPTHPGD
SCHEMBL15423168 0.78 NPC1 (0.55) KDM4EALDH1A1MAPTKDRBACE1
SCHEMBL15316881 0.77 ALDH1A1 (0.35) CYP11B1CYP11B2ALDH1A1CYP19A1KMT2A
SCHEMBL17849691 0.77 ALDH1A1 (0.48) CYP11B1CYP11B2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed