SCHEMBL15423183

SCHEMBL15423183

CC1(C)c2cc(-c3ccc(-c4cn5ccccc5n4)cc3)cc3ccc4cc(-c5cnccn5)cc1c4c23

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 12/20 0.44
NPC1 O15118 10/20 0.44
SMN1; SMN2 Q16637 7/20 0.44
ALDH1A1 P00352 6/20 0.44
PKM P14618 5/20 0.44
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 10/20 0.44
EPHX2 P34913 1/20 0.44
POLB P06746 3/20 0.44
GFER P55789 4/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
HDAC6 Q9UBN7 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
MIF P14174 1/20 0.41
HPGD P15428 3/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423184 0.86 ALDH1A1 (0.50) RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL15423188 0.77 PIM1 (0.39)
SCHEMBL15423165 0.77 CYP2A6 (0.43) RAB9ANPC1SMN1; SMN2ALDH1A1PKM
SCHEMBL15423172 0.76 ABL1 (0.42) SMN1; SMN2ALDH1A1PKMKDM4ETP53
SCHEMBL15423164 0.76 ALDH1A1 (0.53) RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL15423185 0.76 SLC6A2 (0.33) ALDH1A1KDM4EGFERMAPT
SCHEMBL15423169 0.75 SIRT2 (0.42)
SCHEMBL15423174 0.74 BACE1 (0.36) RAB9ANPC1KDM4E
SCHEMBL15423186 0.73 ALDH1A1 (0.45) RAB9ANPC1SMN1; SMN2ALDH1A1MAPK1
SCHEMBL15423187 0.73 RAB9A (0.45) RAB9ANPC1SMN1; SMN2ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed