SCHEMBL15423174

SCHEMBL15423174

CC1(C)c2cc(-c3cnccn3)cc3ccc4cc(-c5cccc(-c6ccncc6)n5)cc1c4c23

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.36
BACE2 Q9Y5Z0 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP19A1 P11511 1/20 0.35
LATS1 O95835 2/20 0.34
ABL1 P00519 3/20 0.34
BCR P11274 2/20 0.33
PIM2 Q9P1W9 2/20 0.33
SRC P12931 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
AR P10275 1/20 0.33
RAB9A P51151 1/20 0.33
LATS2 Q9NRM7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423165 0.86 CYP2A6 (0.43) SLC6A2SLC6A4SLC6A3CYP2D6CYP2C9
SCHEMBL15423172 0.81 ABL1 (0.42) SLC6A2SLC6A4SLC6A3CYP2D6CYP2C9
SCHEMBL15423192 0.79 NPC1 (0.48) BACE1CYP2D6CYP2C9CYP2C19ABL1
SCHEMBL15423171 0.78 TGFBR1 (0.42) ABL1NPC1CYP1A2RAB9ATGFBR1
SCHEMBL15423199 0.77 CYP11B1 (0.40) CYP2D6CYP2C9CYP2C19NPC1CYP1A2
SCHEMBL15423161 0.77 TGFBR1 (0.41) ABL1NPC1RAB9AWNT3ATGFBR1
SCHEMBL15423188 0.76 PIM1 (0.39) BACE1SLC6A2SLC6A4SLC6A3CYP19A1
SCHEMBL15423169 0.76 SIRT2 (0.42) SLC6A2SLC6A4SLC6A3CYP2D6CYP2C9
SCHEMBL15423183 0.74 RAB9A (0.44) NPC1RAB9AKDM4E
SCHEMBL15423184 0.74 ALDH1A1 (0.50) NPC1CYP1A2RAB9APIM1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed