Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15423191 | 0.86 | NPC1 (0.45) | NPC1RAB9APOLBDYRK1APDGFRB | |
| SCHEMBL15423168 | 0.83 | NPC1 (0.55) | NPC1RAB9APOLBDYRK1ATGFBR1 | |
| SCHEMBL15423234 | 0.81 | NPC1 (0.53) | NPC1RAB9APOLBDYRK1AMCL1 | |
| SCHEMBL15423194 | 0.81 | NPC1 (0.40) | NPC1RAB9APOLBDYRK1ATGFBR1 | |
| SCHEMBL15423190 | 0.81 | GRM4 (0.42) | NPC1RAB9APOLBDYRK1ATGFBR1 | |
| SCHEMBL18135290 | 0.81 | NPC1 (0.41) | NPC1RAB9APOLBDYRK1ATGFBR1 | |
| SCHEMBL15423182 | 0.81 | NPC1 (0.49) | NPC1RAB9APOLBDYRK1AMCL1 | |
| SCHEMBL15423193 | 0.79 | NPC1 (0.50) | NPC1RAB9APOLBDYRK1APDGFRB | |
| SCHEMBL15423174 | 0.79 | BACE1 (0.36) | NPC1RAB9ADYRK1ATGFBR1PIK3CD | |
| SCHEMBL15423171 | 0.77 | TGFBR1 (0.42) | NPC1RAB9APOLBTGFBR1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9559310-B2 | Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-01-31 | — | — | US | disclosed |
| US-9559310-B2 | Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-01-31 | — | — | US | disclosed |
| US-20140014925-A1 | NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-01-16 | — | — | US | disclosed |
| US-20140014925-A1 | NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-01-16 | — | — | US | disclosed |