SCHEMBL15423237

SCHEMBL15423237

CC1(C)c2cc(Br)cc3ccc4cc(-c5cc6ccccc6c6ccccc56)cc1c4c23

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.36
ALDH1A1 P00352 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ERBB2 P04626 1/20 0.34
CYP1A2 P05177 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
CYP1B1 Q16678 1/20 0.33
CYP2A6 P11509 1/20 0.32
HPRT1 P00492 1/20 0.31
TRPM4 Q8TD43 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423204 0.82 CYP11B1 (0.40) CYP11B1ALDH1A1HIF1AHSD17B10ERBB2
SCHEMBL15423202 0.81 CYP11B1 (0.43) CYP11B1ALDH1A1HIF1AHSD17B10ERBB2
SCHEMBL15909678 0.80 LPL (0.43) CYP11B1ALDH1A1CYP1A2HPGDNPSR1
SCHEMBL15316881 0.80 ALDH1A1 (0.35) CYP11B1ALDH1A1MAPK1NPSR1CYP2A6
SCHEMBL15423206 0.80 CYP1A2 (0.36) CYP11B1ALDH1A1HIF1AHSD17B10ERBB2
SCHEMBL16168911 0.80 KDM4E (0.35) ALDH1A1CYP1A2ACHEMAPK1L3MBTL1
SCHEMBL15423236 0.79 LPL (0.47) CYP11B1ALDH1A1HIF1AHSD17B10ERBB2
SCHEMBL10034430 0.78 CYP11B1 (0.38) CYP11B1ALDH1A1HIF1AHSD17B10HPGD
SCHEMBL15423199 0.78 CYP11B1 (0.40) CYP11B1ALDH1A1HIF1AHSD17B10ERBB2
SCHEMBL1698290 0.77 NPSR1 (0.35) ALDH1A1NPSR1CYP1B1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed