SCHEMBL15909678

SCHEMBL15909678

CC1(C)c2cc(Br)cc3ccc4cc(-c5ccc6ccccc6c5)cc1c4c23

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
CYP2A6 P11509 1/20 0.43
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALOX5 P09917 1/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
PTGER3 P43115 3/20 0.36
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
GSTP1 P09211 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP17A1 P05093 1/20 0.35
CYP19A1 P11511 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15316881 0.88 ALDH1A1 (0.35) LPLLIPGCYP2A6ESR1ESR2
SCHEMBL17849694 0.85 CYP2A6 (0.41) LPLLIPGCYP2A6ESR1ESR2
SCHEMBL15423234 0.83 NPC1 (0.53) CYP11B1CYP11B2CYP1A2SMN1; SMN2ALDH1A1
SCHEMBL16557798 0.82 CYP2A6 (0.58) LPLLIPGCYP2A6ESR1ESR2
SCHEMBL1698290 0.82 NPSR1 (0.35) CYP2A6ALDH1A1NPSR1KDM4EMAPT
SCHEMBL17849691 0.81 ALDH1A1 (0.48) LPLLIPGESR1ESR2CYP11B1
SCHEMBL15909679 0.81 LPL (0.38) LPLLIPGESR1ESR2ALOX5
SCHEMBL15423237 0.80 CYP11B1 (0.36) CYP2A6CYP11B1CYP1A2ALDH1A1HPGD
SCHEMBL2472869 0.80 CYP2A6 (0.48) LPLLIPGCYP2A6ESR1ESR2
SCHEMBL429952 0.80 CYP2A6 (0.48) LPLLIPGCYP2A6ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed