Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PKLR | P30613 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621923 | 0.85 | L3MBTL1 (0.78) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL12655508 | 0.79 | HTT (0.62) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL12621865 | 0.78 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL12622095 | 0.78 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL15425990 | 0.78 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL16502896 | 0.77 | ALDH1A1 (0.91) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL12624064 | 0.77 | PKM (0.58) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL12623925 | 0.75 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL1722721 | 0.75 | PKM (1.00) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL31315853 | 0.75 | PKM (1.00) | L3MBTL1ALDH1A1KDM4EHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014012054-A1 | ALZHEIMER'S DISEASE ASSAY IN A LIVING PATENT | PAIN THERAPEUTICS, INC. (US) | 2014-01-16 | — | — | WO | disclosed |