Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974120 | 1.00 | ESR1 (0.57) | ESR1ESR2CYP19A1ARMAOA | |
| Flavane SCHEMBL4983060 | 0.93 | ESR1 (0.60) | ESR1ESR2CYP19A1ARMAOA | |
| SCHEMBL4360459 | 0.88 | ESR2 (0.75) | ESR1ESR2CYP19A1ARMAOA | |
| SCHEMBL22882746 | 0.88 | ESR2 (0.75) | ESR1ESR2CYP19A1FFAR1DRD2 | |
| Flavane SCHEMBL26661841 | 0.84 | ESR1 (0.54) | ESR1ESR2CYP19A1ARMAOB | |
| SCHEMBL27944449 | 0.84 | ESR2 (0.56) | ESR1ESR2CYP19A1FFAR1DRD2 | |
| SCHEMBL29974353 | 0.83 | ESR2 (0.71) | ESR1ESR2CYP19A1ARMAOA | |
| SCHEMBL6261080 | 0.83 | ESR2 (0.71) | ESR1ESR2CYP19A1ARMAOA | |
| Flavane SCHEMBL123287 | 0.82 | ESR1 (0.51) | ESR1ESR2CYP19A1ARMAOB | |
| Flavane SCHEMBL14394530 | 0.82 | ESR1 (0.51) | ESR1ESR2CYP19A1ARMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240167066-A1 | METHOD FOR PRODUCING DEMETHYLATED COMPOUND | DAICEL CORPORATION (JP) | 2024-05-23 | — | — | US | disclosed |
| WO-2019238091-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |
| EP-2308565-A2 | ORAL CARE COMPOSITIONS CONTAINING FREE-B-RING FLAVONOIDS AND FLAVANS | Colgate-Palmolive Company (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20060140881-A1 | Oral care compositions containing flavonoids and flavans | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140881-A1 | Oral care compositions containing flavonoids and flavans | APOB, C1QBP, PROC | ESR1 3565/4885ESR2 2498/4885CYP19A1 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.