Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955019 | 0.88 | MEN1 (0.32) | MEN1POLBKMT2AALOX15TP53 | |
| SCHEMBL12573640 | 0.84 | POLB (0.33) | MEN1POLBKMT2AALOX15TP53 | |
| SCHEMBL1956158 | 0.81 | ALDH1A1 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL12573606 | 0.79 | ANO1 (0.33) | MEN1KMT2AP2RX7 | |
| SCHEMBL6850218 | 0.79 | PYGL (0.42) | MEN1POLBKMT2A | |
| SCHEMBL6762557 | 0.76 | ALOX15 (0.42) | MEN1POLBKMT2AALOX15TP53 | |
| SCHEMBL12573604 | 0.75 | KMT2A (0.34) | MEN1POLBKMT2AALOX15P2RX7 | |
| SCHEMBL6850976 | 0.74 | ALOX15 (0.40) | MEN1POLBKMT2AALOX15TP53 | |
| SCHEMBL37248 | 0.73 | EPHX2 (0.33) | MEN1POLBKMT2AALOX15TP53 | |
| SCHEMBL12573637 | 0.72 | HRH3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507240-B1 | SPIRO FUSED 1-AMINO-PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-15 | — | — | EP | disclosed |