Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611200 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNABTKSMN1; SMN2NPC1 | |
| SCHEMBL15425997 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNAGRM5MAPK14BRPF1 | |
| SCHEMBL2035901 | 0.74 | CLEC4M (0.55) | ALDH1A1TP53MAPT | |
| SCHEMBL12700469 | 0.70 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12610974 | 0.68 | SMN1; SMN2 (0.51) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2488117 | 0.68 | CLEC4M (0.53) | ALDH1A1TP53MAPT | |
| SCHEMBL14104483 | 0.67 | HSD17B10 (0.64) | ALDH1A1LMNASMN1; SMN2RAB9ATP53 | |
| SCHEMBL17193970 | 0.66 | MAPT (0.54) | ALDH1A1NPC1NPSR1LTA4HMAPT | |
| SCHEMBL20157554 | 0.66 | MAPT (0.54) | ALDH1A1LMNASMN1; SMN2NPC1TP53 | |
| SCHEMBL23884587 | 0.66 | MAPT (0.50) | LMNAGRM5MAPK14SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018384-A1 | QUINOLINONE DERIVATIVES FOR USE IN THE TREATMENT OF AN AUTOIMMUNE DISEASE AND/OR AN INFLAMMATORY DISEASE | PRONOXIS AB (SE) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018384-A1 | QUINOLINONE DERIVATIVES FOR USE IN THE TREATMENT OF AN AUTOIMMUNE DISEASE AND/OR AN INFLAMMATORY DISEASE | NOX4, NOX1, CYBB | ALDH1A1 517/4885LMNA 3790/4885BTK 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.