Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611200 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNACNR1CNR2GAA | |
| SCHEMBL12610974 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1LMNAGAANPSR1MAPT | |
| SCHEMBL13555236 | 0.72 | CYP3A4 (0.41) | ALDH1A1CNR1CNR2GAAMAPT | |
| SCHEMBL10839866 | 0.70 | KDM4E (0.65) | ALDH1A1CNR1CNR2MAPTHTT | |
| SCHEMBL15425995 | 0.70 | ALDH1A1 (0.49) | ALDH1A1LMNANPSR1MAPTSMN1; SMN2 | |
| SCHEMBL15425997 | 0.67 | ALDH1A1 (0.45) | ALDH1A1LMNANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL10498740 | 0.67 | ALDH1A1 (0.76) | ALDH1A1LMNACNR2NPSR1MAPT | |
| SCHEMBL1584218 | 0.66 | RAB9A (0.67) | ALDH1A1LMNACNR2GAANPSR1 | |
| SCHEMBL31286496 | 0.66 | RAB9A (0.67) | ALDH1A1LMNACNR2GAANPSR1 | |
| SCHEMBL1563066 | 0.66 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012127214-A1 | QUINOLINONE DERIVATIVES FOR USE IN THE TREATMENT OF AN AUTOIMMUNE DISEASE AND/OR AN INFLAMMATORY DISEASE | PRONOXIS AB (SE) | 2012-09-27 | — | — | WO | disclosed |