Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.49 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486082 | 0.89 | HTT (0.60) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL15426073 | 0.88 | HTT (0.63) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486597 | 0.85 | HTT (0.87) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL15426103 | 0.84 | KDM7A (0.55) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL16363115 | 0.84 | HTT (0.63) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL16363114 | 0.83 | HTT (0.60) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL4567254 | 0.83 | KDM5A (0.58) | KDM7A | |
| SCHEMBL17364506 | 0.83 | HTT (0.75) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL15426085 | 0.82 | KDM7A (0.53) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486241 | 0.82 | HTT (0.86) | HTTMAPK1TDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024046-B2 | Reductive amination process for preparation of dronedarone using amine intermediary compound | SANOFI (FR) | 2015-05-05 | — | — | US | disclosed |