Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281012 | 0.93 | HSD11B1 (0.52) | HSD11B1PIK3CAPIK3CBPIK3CGPDE2A | |
| SCHEMBL15426449 | 0.81 | PIK3CA (0.42) | PIK3CAPIK3CBPIK3CGPDE2APDE10A | |
| SCHEMBL15426450 | 0.80 | DDR1 (0.44) | PIK3CAPIK3CBPIK3CGPDE2AAGPAT2 | |
| SCHEMBL167106 | 0.80 | PDE10A (0.46) | HSD11B1PIK3CAPIK3CBPIK3CGPDE2A | |
| SCHEMBL15426486 | 0.80 | HSD11B1 (0.47) | HSD11B1PDE2APDE10AMPLMCHR1 | |
| SCHEMBL15426448 | 0.79 | PIK3CA (0.41) | PIK3CAPIK3CBPIK3CGAGPAT2ACSS2 | |
| SCHEMBL15426505 | 0.79 | HSD11B1 (0.46) | HSD11B1PDE2APDE10AMPLGRM2 | |
| SCHEMBL355769 | 0.78 | PDE2A (0.44) | HSD11B1PIK3CAPIK3CBPIK3CGPDE2A | |
| SCHEMBL24397667 | 0.77 | PDE2A (0.46) | HSD11B1PIK3CAPIK3CBPIK3CGPDE2A | |
| SCHEMBL29497618 | 0.77 | PDE2A (0.46) | HSD11B1PIK3CAPIK3CBPIK3CGPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278983-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8853238-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20140018373-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018373-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | NR4A1, NR2C2, NR0B1 | HSD11B1 1704/4885PIK3CA 4291/4885PIK3CB 4032/4885 |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR4A1, NR2C2, NR0B1 | HSD11B1 1639/4885PIK3CA 4183/4885PIK3CB 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.