Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 6/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.37 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281176 | 0.91 | HSD11B1 (0.47) | HSD11B1MPLFEN1ALOX5APPDE2A | |
| SCHEMBL15426497 | 0.79 | HSD11B1 (0.49) | HSD11B1MPLPDE2APDE10AGRM2 | |
| SCHEMBL10281012 | 0.77 | HSD11B1 (0.52) | HSD11B1MPLPDE2APDE10AGRM2 | |
| SCHEMBL15426486 | 0.77 | HSD11B1 (0.47) | HSD11B1MPLFEN1ALOX5APPDE2A | |
| SCHEMBL16280605 | 0.72 | HSD11B1 (0.48) | HSD11B1MPLPDE2APDE10AGRM2 | |
| SCHEMBL10280804 | 0.72 | HSD11B1 (0.48) | HSD11B1MPLFEN1ALOX5APPDE2A | |
| SCHEMBL16064958 | 0.72 | HSD11B1 (0.50) | HSD11B1MPLPDE2APDE10AGRM2 | |
| SCHEMBL9953119 | 0.67 | SLC6A2 (0.38) | HSD11B1FEN1ALOX5APPDE2APDE10A | |
| SCHEMBL10280803 | 0.67 | POLB (0.43) | HSD11B1PDE2APDE10AGRM2 | |
| SCHEMBL29755473 | 0.65 | HSD11B1 (0.51) | HSD11B1MPLFEN1ALOX5APPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278983-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8853238-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20140018373-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018373-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | NR4A1, NR2C2, NR0B1 | HSD11B1 1704/4885MPL 4785/4885FEN1 3336/4885 |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR4A1, NR2C2, NR0B1 | HSD11B1 1639/4885MPL 4784/4885FEN1 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.