Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172467 | 0.81 | BCHE (0.62) | ALDH1A1BCHEACHESNCASIGMAR1 | |
| SCHEMBL10401164 | 0.79 | ALDH1A1 (0.64) | ALDH1A1BCHEACHESIGMAR1LMNA | |
| Butylbenzyl SCHEMBL25373904 | 0.79 | SIGMAR1 (0.59) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL20512380 | 0.78 | BCHE (0.54) | ALDH1A1BCHEACHESNCALMNA | |
| SCHEMBL27782985 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL29350218 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28031451 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6398343 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6686635 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL30668793 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108930-B2 | N1- and N2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140018318-A1 | N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS | THE SCIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018318-A1 | N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS | PRSS1, PRSS3, CES1 | ALDH1A1 1042/4885BCHE 5/4885ACHE 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.