Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655999 | 0.93 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2AALDH1A1PRCP | |
| SCHEMBL12621946 | 0.88 | L3MBTL1 (0.61) | L3MBTL1MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL12623940 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL12621942 | 0.80 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL15423912 | 0.80 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2AALDH1A1HTR1A | |
| SCHEMBL15693684 | 0.79 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL12621923 | 0.78 | L3MBTL1 (0.78) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL12655986 | 0.78 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL12622049 | 0.76 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1 | |
| SCHEMBL12621863 | 0.76 | LMNA (0.62) | L3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9500640-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140017699-A1 | ALZHEIMER'S DISEASE ASSAY IN A LIVING PATIENT | CASSAVA SCIENCES, INC. | 2014-01-16 | — | — | US | disclosed |