Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 18/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22259417 | 0.79 | ALDH1A1 (0.41) | BRD4P2RX7 | |
| SCHEMBL15427281 | 0.79 | MEN1 (0.41) | BRD4P2RX7LMNA | |
| SCHEMBL15621584 | 0.76 | LMNA (0.56) | BRD4P2RX7LMNA | |
| SCHEMBL19116500 | 0.76 | SMN1; SMN2 (0.42) | BRD4P2RX7LMNA | |
| SCHEMBL28521208 | 0.76 | P2RX7 (0.39) | BRD4P2RX7 | |
| SCHEMBL19151155 | 0.75 | LMNA (0.42) | BRD4P2RX7LMNA | |
| SCHEMBL22449838 | 0.75 | ALDH1A1 (0.41) | BRD4P2RX7LMNA | |
| SCHEMBL15617686 | 0.75 | HPGD (0.37) | BRD4P2RX7LMNA | |
| SCHEMBL15932513 | 0.74 | ALDH1A1 (0.39) | BRD4P2RX7 | |
| SCHEMBL20888086 | 0.74 | TSHR (0.45) | BRD4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870153-B1 | SULFONYL CONTAINING BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2014011513-A1 | SULFONYL CONTAINING BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-01-16 | — | — | WO | disclosed |