⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435246 | 0.83 | PRMT3 (0.39) | — | |
| SCHEMBL21099551 | 0.81 | EPHX1 (0.41) | — | |
| SCHEMBL18016998 | 0.78 | PRMT3 (0.34) | — | |
| SCHEMBL8746589 | 0.77 | — | — | |
| SCHEMBL1831649 | 0.77 | — | — | |
| SCHEMBL15830449 | 0.77 | — | — | |
| SCHEMBL16676987 | 0.77 | PRMT3 (0.33) | — | |
| SCHEMBL9814035 | 0.76 | TSHR (0.47) | — | |
| SCHEMBL4686373 | 0.76 | PRMT3 (0.46) | — | |
| SCHEMBL1829312 | 0.75 | ADH1B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069747-A | Method for synthesizing N-heterocyclic carbene complex by utilizing hydrolysate of imidazole salt | 石河子大学 | 2023-11-17 | — | — | CN | claimed |
| EP-4267194-A1 | TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES | SOTIO Biotech a.s. (CZ) | 2023-11-01 | — | — | EP | claimed |
| CN-116635085-A | Tumor specific claudin 18.2 antibody-drug conjugate | 斯迪安生物技术公司 | 2023-08-22 | — | — | CN | claimed |
| WO-2022136642-A1 | TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES | Sotio Biotech A.S. (CZ) | 2022-06-30 | — | — | WO | claimed |
| WO-2022122709-A1 | ANTIBODY-DRUG CONJUGATES BASED ON HUMANIZED CLDN18.2 ANTIBODIES | Sotio Biotech A.S. (CZ) | 2022-06-16 | — | — | WO | claimed |
| WO-2025078686-A1 | COMBINATION THERAPY INVOLVING ANTIBODY-DRUG CONJUGATES AGAINST CLAUDIN18.2 AND PD1/PD-L AXIS INHIBITORS FOR TREATMENT OF CANCER | Sotio Biotech A.S. (CZ) | 2025-04-17 | — | — | WO | disclosed |
| CN-117069747-A | Method for synthesizing N-heterocyclic carbene complex by utilizing hydrolysate of imidazole salt | 石河子大学 | 2023-11-17 | — | — | CN | disclosed |
| EP-4267194-A1 | TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES | SOTIO Biotech a.s. (CZ) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| CN-116635085-A | Tumor specific claudin 18.2 antibody-drug conjugate | 斯迪安生物技术公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-112830449-B | Reversible liquid organic hydrogen storage method based on manganese catalytic hydrogenation and dehydrogenation reaction | 清华大学 | 2022-09-27 | — | — | CN | disclosed |
| WO-2022136642-A1 | TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES | Sotio Biotech A.S. (CZ) | 2022-06-30 | — | — | WO | disclosed |
| CN-1708817-A | Electrolytic solution for electrolytic capacitor, and method for producing tetrafluoroaluminate salt of organic onium | MITSUBISHI CHEM CORP (JP) | 2005-12-14 | — | — | CN | disclosed |
| US-20050222368-A1 | Aqueous polyurethane dispersions | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | US | disclosed |
| EP-1564768-A1 | ELECTROLYTE FOR ELECTROLYTIC CAPACITOR, ELECTROLYTIC CAPACITOR AND PROCESS FOR PRODUCING TETRAFLUOROALUMINATE SALT OF ORGANIC ONIUM | Mitsubishi Chemical Corporation (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-0807105-B1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6284836-B1 | COATINGS FOR WOOD, TEXTILE, PAPER, PLASTIC, METAL, OR LEATHER. | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |