Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880724 | 0.81 | PDK2 (0.40) | HTR5APDK2PDK4HTR2A | |
| SCHEMBL24701676 | 0.76 | PDK2 (0.33) | PDK2 | |
| SCHEMBL29683228 | 0.75 | PDK2 (0.37) | HTR5APDK2PDK4HTR2A | |
| SCHEMBL942269 | 0.75 | PDK2 (0.37) | HTR5APDK2PDK4HTR2A | |
| SCHEMBL24701668 | 0.72 | TDP1 (0.36) | PDK2HTR2AHTR2C | |
| SCHEMBL22202632 | 0.71 | PDK2 (0.34) | HTR5APDK2PDK4HTR2A | |
| SCHEMBL16388852 | 0.69 | PDK2 (0.35) | PDK2 | |
| SCHEMBL22015646 | 0.69 | PDK2 (0.35) | PDK2 | |
| SCHEMBL22655432 | 0.69 | PDK2 (0.41) | PDK2 | |
| SCHEMBL24314083 | 0.69 | PDK2 (0.46) | PDK2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3424936-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-2935293-B1 | IRIDIUM COMPLEXES AND THEIR USE IN ELECTRONIC DEVICES, ESPECIALLY ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20150318498-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| WO-2015117718-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | WO | disclosed |
| WO-2015104045-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| WO-2014094962-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014023377-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014008982-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HTR5A 2846/4885PDK2 3655/4885PDK4 3693/4885 |
| US-20150318498-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | HTR5A 4536/4885PDK2 2330/4885PDK4 2670/4885 |
| US-20150263297-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | HTR5A 4536/4885PDK2 2330/4885PDK4 2670/4885 |
| US-20150171348-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | HTR5A 4536/4885PDK2 2330/4885PDK4 2670/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | HTR5A 4536/4885PDK2 2330/4885PDK4 2670/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HTR5A 4551/4885PDK2 2111/4885PDK4 2684/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | HTR5A 4582/4885PDK2 3019/4885PDK4 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.