SCHEMBL22655432

SCHEMBL22655432

CC1(C)c2ccccc2-c2ccccc2C1(F)F

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 11/20 0.41
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
S100A4 P26447 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
OPRK1 P41145 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386757 0.82 PDK2 (0.44) PDK2THRBTDP1S100A4KDM4E
SCHEMBL18383337 0.82 PDK2 (0.44) PDK2THRBTDP1S100A4KDM4E
SCHEMBL6316881 0.82 PDK2 (0.50) PDK2THRBTDP1S100A4KDM4E
SCHEMBL29608923 0.82 PDK2 (0.50) PDK2THRBTDP1S100A4KDM4E
SCHEMBL2820392 0.80 ALDH1A1 (0.44) PDK2THRBTDP1S100A4KDM4E
SCHEMBL24314083 0.77 PDK2 (0.46) PDK2THRBTDP1S100A4KDM4E
SCHEMBL22782728 0.73 PGR (0.34) PDK2TDP1MEN1LMNAMAPT
SCHEMBL22238454 0.73 ALDH1A1 (0.35) PDK2KDM4ETSHR
SCHEMBL21198046 0.72 THRB (0.38) PDK2THRBTDP1KDM4E
SCHEMBL23936829 0.71 PDK2 (0.46) PDK2THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417415-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-19 US disclosed
US-12103942-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-01 US disclosed
US-20200361974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-19 US disclosed
CN-111925397-A Organic electroluminescent material and device 环球展览公司 2020-11-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240417415-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, TRPM2, ORAI2 PDK2 1845/4885THRB 3487/4885TDP1 2190/4885
US-12103942-B2 Organic electroluminescent materials and devices L1CAM, TRPM2, ORAI2 PDK2 1845/4885THRB 3487/4885TDP1 2190/4885
US-20200361974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, TRPM2, ORAI2 PDK2 1845/4885THRB 3487/4885TDP1 2190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.