Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428164 | 0.98 | AVPR1A (0.44) | AVPR1ASLC6A2SLC6A4SLC6A3PDE7A | |
| SCHEMBL25628434 | 0.91 | AVPR1A (0.47) | AVPR1A | |
| SCHEMBL738649 | 0.84 | SIGMAR1 (0.46) | AVPR1ASLC6A2SLC6A4 | |
| SCHEMBL30485367 | 0.81 | AVPR1A (0.47) | AVPR1A | |
| SCHEMBL6264633 | 0.81 | AVPR1A (0.47) | AVPR1A | |
| SCHEMBL4979408 | 0.81 | AVPR1A (0.53) | AVPR1A | |
| SCHEMBL20629522 | 0.80 | AVPR1A (0.49) | AVPR1A | |
| SCHEMBL16768499 | 0.77 | CYP2D6 (0.47) | AVPR1A | |
| SCHEMBL10819385 | 0.77 | AVPR1A (0.47) | AVPR1A | |
| SCHEMBL8121303 | 0.77 | PDK2 (0.36) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3424936-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| EP-3094638-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| WO-2015104045-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| WO-2014023377-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014008982-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150263297-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | AVPR1A 2910/4885SLC6A2 2243/4885SLC6A4 2877/4885 |
| US-20150171348-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | AVPR1A 2910/4885SLC6A2 2243/4885SLC6A4 2877/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | AVPR1A 2910/4885SLC6A2 2243/4885SLC6A4 2877/4885 |
| US-20160365520-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | AVPR1A 2910/4885SLC6A2 2243/4885SLC6A4 2877/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | AVPR1A 2791/4885SLC6A2 2149/4885SLC6A4 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.