SCHEMBL15430205

SCHEMBL15430205

Cc1cccc(C2C(=O)Oc3c2cc(CCC(=O)OCCOCCOCCOC(=O)CCc2cc4c(c(C(C)(C)C)c2)OC(=O)C4c2cccc(C)c2)cc3C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
ALOX5 P09917 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430381 0.91 TDP1 (0.40) GAAALDH1A1MAPTALOX5KDM4E
SCHEMBL19320501 0.90 P2RY10 (0.36) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL19320498 0.90 P2RY10 (0.36) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL19320502 0.90 GAA (0.39) GAAALDH1A1MAPTKDM4EMEN1
SCHEMBL19320499 0.88 GAA (0.36) GAAALDH1A1MAPTKDM4EMEN1
SCHEMBL19909643 0.85 ALOX5 (0.36) GAAALDH1A1ALOX5KDM4ETDP1
SCHEMBL15430188 0.84 ALOX5 (0.40) GAAALOX5TDP1
SCHEMBL16883688 0.84 GAA (0.33) GAAALOX5MEN1KMT2ATDP1
SCHEMBL19320500 0.83 CYP3A4 (0.38) GAAALDH1A1MAPTKDM4EMEN1
SCHEMBL16883645 0.80 GAA (0.32) GAAALOX5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328218-B2 Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material BASF SE (DE) 2016-05-03 US disclosed
US-9328218-B2 Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material BASF SE (DE) 2016-05-03 US disclosed
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2015-07-09 US disclosed
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2015-07-09 US disclosed
WO-2014009361-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2014-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL H1-0, PCBP1, HEATR1 GAA 624/4885ALDH1A1 170/4885MAPT 835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.