Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909643 | 0.94 | ALOX5 (0.36) | TDP1ALOX5GAAAPPALDH1A1 | |
| SCHEMBL15430188 | 0.93 | ALOX5 (0.40) | TDP1ALOX5GAAAPP | |
| SCHEMBL15430205 | 0.91 | GAA (0.35) | TDP1ALOX5GAAALDH1A1KMT2A | |
| SCHEMBL19894685 | 0.89 | ALOX5 (0.37) | TDP1ALOX5GAAAPP | |
| SCHEMBL19909635 | 0.89 | ALOX5 (0.37) | TDP1ALOX5GAAAPPALDH1A1 | |
| SCHEMBL6075102 | 0.87 | GAA (0.39) | GAAALDH1A1MAOBKMT2AMAOA | |
| SCHEMBL16883688 | 0.85 | GAA (0.33) | TDP1ALOX5GAAAPPKMT2A | |
| SCHEMBL19909634 | 0.84 | ALOX5 (0.33) | TDP1ALOX5GAA | |
| SCHEMBL16883645 | 0.82 | GAA (0.32) | ALOX5GAAKMT2AHTT | |
| SCHEMBL17714669 | 0.82 | GAA (0.32) | ALOX5GAAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872496-B1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL]DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-9328218-B2 | Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material | BASF SE (DE) | 2016-05-03 | — | — | US | disclosed |
| US-9328218-B2 | Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material | BASF SE (DE) | 2016-05-03 | — | — | US | disclosed |
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2015-07-09 | — | — | US | disclosed |
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2015-07-09 | — | — | US | disclosed |
| WO-2014009361-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | H1-0, PCBP1, HEATR1 | TDP1 1311/4885ALOX5 1849/4885GAA 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.