Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 5/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15430340 | 0.93 | PLA2G2A (0.33) | CCNE1CDK2TACR1PRKDCPLA2G2A | |
| SCHEMBL15430338 | 0.91 | PRKDC (0.36) | CCNE1CDK2TACR1PRKDCPIK3CA | |
| SCHEMBL15430264 | 0.85 | CCNE1 (0.34) | CCNE1CDK2TACR1PIK3CACHEK1 | |
| SCHEMBL15430337 | 0.85 | PRKDC (0.32) | PRKDC | |
| SCHEMBL15430302 | 0.84 | ALOX5 (0.43) | PRKDCPLA2G2APLA2G4APLA2G10 | |
| SCHEMBL15430304 | 0.84 | ALOX5 (0.46) | PRKDCPLA2G2APLA2G4APLA2G10 | |
| SCHEMBL13309571 | 0.84 | TACR1 (0.41) | CCNE1CDK2TACR1PIK3CACHEK1 | |
| SCHEMBL15430345 | 0.83 | PRKDC (0.36) | TACR1PRKDCCDK8ROCK1 | |
| SCHEMBL15430298 | 0.83 | ALOX5 (0.46) | PRKDCPLA2G2APLA2G4APLA2G10 | |
| SCHEMBL15430305 | 0.83 | ALOX5 (0.46) | PRKDCPLA2G2APLA2G4APLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140014930-A1 | Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20140014930-A1 | Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20070037979-A1 | Preparation of rosuvastatin | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037979-A1 | Preparation of rosuvastatin | HMGCR, PCSK9, PCSK7 | CCNE1 3180/4885CDK2 1540/4885TACR1 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.