SCHEMBL15433182

SCHEMBL15433182

CC/C(F)=C(\F)c1ccc(-c2ccc(-c3cc(F)c(F)c(F)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 16/20 0.40
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KIF11 P52732 1/20 0.34
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433383 1.00 ANPEP (0.40) ANPEPRXRARXRBKDM4ELMNA
SCHEMBL15433538 0.92 RARB (0.38) ANPEPRXRARXRB
SCHEMBL15433387 0.89 RARB (0.36) ANPEPKDM4ELMNAHSD17B10KIF11
SCHEMBL15433170 0.89 RARB (0.36) ANPEPKDM4ELMNAHSD17B10KIF11
SCHEMBL15433179 0.89 RARB (0.36) ANPEPKDM4ELMNAHSD17B10KIF11
SCHEMBL15433181 0.88 RARB (0.40) ANPEP
SCHEMBL15433395 0.87 ANPEP (0.34) ANPEP
SCHEMBL15433233 0.85 KIF11 (0.32) ANPEPRXRARXRBKDM4ELMNA
SCHEMBL15433672 0.85 MAOB (0.39) ANPEP
SCHEMBL15433831 0.84 RARB (0.33) ANPEPKDM4ELMNAHSD17B10KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed